코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Beauvericin

함유 천연물 

Beauveria bassiana (Bals.) Vuill.[-]()

분 자 식 

C₄₅H₅₇N₃O₉

화학족 분류 

단백질(protein);

분 자 량 

783.971

녹 는 점 

93-94°C MeOH aq.

생리학적효과 

Acyl-Co A: cholesterol acyltransferase inhibitor. Antifungal agent, active against insects. Induces apoptosis via elevation of cytoplasmic Ca.

굴 절 율 

[α]25 D = +65.8° (C 1,MeOH)

UV_CHART 

(λmax, nm) (EtOH):204(13550), 248(1320), 256(1140), 263(870)

HNMR_CHART 

(CDCl3) δ:3.04(s), 0.4(d,7.5,Me), 0.8(d,7.5,Me), 1.95(m), 4.87(d), 7.25, 3.02 & 3.39(AB protons), 5.60(q,12.1,5.0)

MASS_CHART 

M+= 783

참고문헌 

· M. Gorman et al., Tetrahedron Lett., 4255, 1969(uv,ir,pmr) · S. Tamura et al., Tetrahedron Lett., 2167, 1977 · YuA. Ovchinnikov et al., Tetrahedron Lett., 159, 1971 · M. Bernardini et al., Phytochemistry, 14, 1865, 1975 · AJ. Geddes et al., Acta Cryst. B, 32, 3164, 1976 · BS. Deol et al., Aust. J. Chem., 31, 1397, 1978 · BC. Braden, Diss. Abstr. Int., B, 39, 2094, 1978 · B. Braden et al., J. Am. Chem. Soc., 102, 2704, 1980 · M. Abu Khaled et al., Biochim. Biophys. Acta, 704, 186, 1982(pmr) · LK. Steinrauf, Met. Ions Biol. Syst., 19, 139, 1985 · DM. Ojcius et al., Exp. Cell Res., 197, 43, 1991 · H. Tomoda et al., J. Antibiot., 45, 1626, 1992 · RD. Plattner et al., Appl. Environ. Microbiol., 60, 3894, 1994