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▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
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성 분 명 |
Dihydrosanguinarine |
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다른이름들 |
13,14-Dihydro-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]-phenanthridine |
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함유 천연물 |
Chelidonium majus L.[]()
Coptis chinensis Franch.[](황련(黃連))
Papaver somniferum L.[양귀비(Yang-gwi-bi)](앵속각(罌粟殼)) |
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분 자 식 |
C20H15NO4 |
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화학족 분류 |
알칼로이드(alkaloid); |
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분 자 량 |
333.347 |
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녹 는 점 |
195-196°C CHCl3/MeOH |
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UV_CHART |
(λmax, nm) (EtOH):237(4.55), 284(4.57), 322(4.21), 335 sh(4.12), 350 sh(3.72); (EtOH-0.1N HCl): 238(4.53), 250 sh(4.49), 265(4.40), 274(4.40), 307(4.20), 321(4.36), 338(4.20), 355(4.30) |
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HNMR_CHART |
(CDCl3,100 MHz) δ:7.72(1H, s, H1), 7.10(1H, s, H4), 7.46(1H, d, 9, H5), 7.69(1H, d, 9, H6), 4.14(1H, s, H8), 6.83(1H, d, 8, H11), 7.30(1H, d, 8, H12), 2.54(3H, s, NMe), 5.99(2H, s, OCH2O), 5.99(2H, s, OCH2O) |
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MASS_CHART |
M+= 333, m/z= 332, 318, 274, 239, 201 |
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참고문헌 |
· RHF. Manske, Can. J. Res., Sect. B, 21, 140, 1943
· BD. Krane et al., J. Nat. Prod., 47, 1, 1984(uv,ir,pmr,ms)
· L. Slavikova et al., Coll. Czech. Chem. Comm., 21, 211, 1956
· DB. MacLean et al., Can. J. Chem., 47, 1951, 1969
· M. Onda et al., Chem. Pharm. Bull., 18, 1435, 1970
· FR. Stermitz et al., Phytochemistry, 11, 2644, 1972
· T. Furuya et al., Phytochemistry, 11, 3041, 1972
· A. Ikuta et al., Phytochemistry, 13, 2175, 1974; 15, 577, 1976
· N. Takao et al., Chem. Pharm. Bull., 24, 2859, 1976
· J. Slavik et al., Coll. Czech. Chem. Comm., 42, 2686, 1977
· M. Hanaoka et al., Chem. Lett., 739, 1986
· T. Tanahashi et al., Tetrahedron Lett., 29, 5625, 1988 |
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