코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Datumetine

다른이름들 

O-(4-Methoxybenzoyl)-3-tropanol (endo-form) O-(4-Methoxybenzoyl)-8-methyl-8-azabicyclo-[3.2.1]octan-3-ol (endo-form)

함유 천연물 

Datura alba Rumph.ex Nees[]()
Datura meteloides Dunal[털독말풀(Teol-dok-mal-pul)](양금화(洋金花),만타라자(曼陀羅子))

분 자 식 

C₁₆H₂₁NO₃

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

275.351

녹 는 점 

84°C CHCl3/Et2O

UV_CHART 

(λmax, nm) (MeOH):213, 253, 257, 258

HNMR_CHART 

(CDCl3) δ:3.8(3H, s, OCH3), 2.2(3H, s, N-CH3), 5.2(1H, t, H3), 3.17(2H, br s, H1,5), 2.08(4H, br s, H2,4), 1.83(2H, d, H6a,7a), 2.25(2H, dt, H6b,7b), 6.9(2H, dd, H2',6'), 7.9(2H, H3',5')

MASS_CHART 

M+= 275, m/z= 151, 140, 135, 124, 107, 96, 94, 83, 82

참고문헌 

· S. Siddiqui et al., J. Nat. Prod., 49, 511, 1986 · L. Witte et al., Planta Med., 5, 390, 1986(ms) · WC. Evans et al., J. Chem. Soc., 1406, 1959 · H. Schenk et al., Acta Cryst., 23, 423, 1967 · JW. Loder et al., Aust. J. Chem., 22, 1271, 1969 · GS. Chappell et al., J. Pharm. Sci., 62, 414, 1973 · P. Hanish et al., J. Chem. Soc. Perkin 2, 1202, 1977 · HF. Grutzmacher et al., Chem. Ber., 111, 1962, 1978 · Y. Hayakawa et al., J. Am. Chem. Soc., 100, 1786, 1978 · JJ. Tufariello et al., J. Am. Chem. Soc., 101, 2435, 1979 · H. Iida et al., J. Org. Chem., 50, 1818, 1985 · M. Lounasmaa, Alkaloids (N.Y.), 33, 1, 1988