코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Corlumidine {(+)-form),(1S,9R-form)}

다른이름들 

6-(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one; 7-O-De-Me Corlumine; 7-O-De-Me

함유 천연물 

Corydalis decumbens (Thunb.) Pers.[좀현호색(Jom-hyeon-ho-saek)](하천무(夏天無))
Corydalis yanhusuo W. T. Wang[](연호색(延胡索))

분 자 식 

C₂₀H₁₉NO₆

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

369.378

녹 는 점 

236°C CHCl3 or MeOH

생리학적효과 

GABA antagonist. Convulsive agent.

굴 절 율 

[α]23 D = +80° (C 0.4,CHCl3)

UV_CHART 

(λmax, nm) :288(3.70), 320(3.73)

참고문헌 

· RHF. Manske, Can. J. Res., Sect. B, 14, 347, 1936 · G. Blasko et al., J. Nat. Prod., 44, 475, 1981 · M. Shamma et al., Tetrahedron Lett., 2339, 1974 · OE. Edwards et al., Can. J. Chem., 39, 1801, 1961 · S. Safe et al., Can. J. Chem., 42, 160, 1964 · K. Blaha et al., Coll. Czech. Chem. Comm., 29, 2328, 1964 · MS. Yunusov et al., Khim. Prir. Soedin., 4, 61, 1968; Chem. Nat. Compd. (Engl. Transl.), 4, 54, 1968 · G. Snatzke et al., Tetrahedron, 25, 5059, 1969 · IA. Israilov et al., Khim. Prir. Soedin., 11, 612, 811, 1975; 14, 103, 465, 1978; Chem. Nat. Compd. (Engl. Transl.), 11, 1975 · DW. Hughes et al., Can. J. Chem., 54, 2252, 1976(cmr) · BC. Nalliah et al., Can. J. Chem., 57, 1546, 1979 · IMP. Huber et al., Helv. Chim. Acta, 70, 1944, 1987 · Atta-ur-Rahman et al., Heterocycles, 29, 1091, 1989