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 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Coptisine

다른이름들 

2,3:9,10-Bismethylenedioxyprotoberberine 6,7-Dihydrobis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizinium

함유 천연물 

Chelidonium majus L.[]()
Coptis chinensis Franch.[](황련(黃連))
Coptis deltoidea C. Y. Cheng et Hsiao[](황련(黃連))
Coptis japonica (Thunb.) Makino[황련(Hwangn-yeon)](황련(黃連))
Coptis teeta[]()
Corydalis yanhusuo W. T. Wang[](연호색(延胡索))
Nandina domestica Thunb.[남천(Nam-cheon)](남천죽자(南天竹子),남천죽엽(南天竹葉),남천죽근(南天竹根))
Papaver somniferum L.[양귀비(Yang-gwi-bi)](앵속각(罌粟殼))
Phellodendron amurense Rupr.[황벽나무(Hwang-byeok-na-mu)](황백(黃柏))
Phellodendron chinense Schneid.[](황백(黃柏),황벽(黃蘗))

분 자 식 

C₁₉H₁₄NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

320.328

녹 는 점 

(OH) 216-218°C

생리학적효과 

Antiinflammatory agent. Uterine contractant.

UV_CHART 

(λmax, nm) (EtOH):237(3.85), 289(3.89)

HNMR_CHART 

(TFA,100 MHz) δ:(Cl); 7.46(s, H1), 6.91(s, H4), 9.41(s, H8), 7.81(s, H11,12), 8.46(s, H13), 3.90(s, 2,3-OCH2O), 3.56(s, 9,10-OCH2O)

참고문헌 

· Huang-Minlon, Ber., 69, 1737, 1936 · SF. Cooper et al., Planta Med., 21, 313, 1972(uv) · K. Jewers et al., J. Chem. Soc. Perkin Trans. 2, 1393, 1972 · A. Ikuta et al., Phytochemistry, 27, 7, 2143, 1988 · S. Pavelka et al., Collect. Czech. Chem. Commun., 41, 3157, 1976