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 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Anagyrine ((-)-form)

다른이름들 

7,7a,8,9,10,11,13,14-Octahydro-7,14-methano-4H,6H-dipyrido-[1,2-a;1',2'-e][1,5]diazocin-4-one Alkaloid III Monolupine Rhombinine

함유 천연물 

Sophora alopecuroides L.[-]()
Sophora arizonica S. Wats.[-]()
Sophora chrysophylla Seem.[-]()
Sophora exigua[-]()
Sophora flavescens Solander ex Aiton[고삼(Go-sam)](고삼(苦蔘),고삼실(苦蔘實),수괴(水槐),지괴(地槐))
Sophora formosa[-]()
Sophora franchetiana Dunn[-]()
Sophora griffithii[-]()
Sophora gysophylla B.L. Turner & Powell[-]()
Sophora japonica L.[회화나무(Hoe-hwa-na-mu)](괴화(槐花),괴각(槐角),괴지(槐枝),괴엽(槐葉),괴각자(槐角子),괴교(槐膠),괴근백피(槐根白皮),괴백피(槐白皮),괴실(槐實),괴윤(槐潤),괴자(槐子),괴자인(槐子仁),괴조(槐條),수궁괴(守宮槐))
Sophora leachiana M.E. Peck[-]()
Sophora longesmen[-]()
Sophora macrocarpa[-]()
Sophora masafeurana[-]()
Sophora microphylla[-]()
Sophora mollis[-]()
Sophora moorcroftiana (Wall.) Benth.ex Bak.[-]()
Sophora muteliana[-]()
Sophora secundiflora (Ortega) Lag.ex DC.[]()
Sophora stenophylla Gray[-]()
Sophora subprostrata Chun et T. Chen[광두근](산두근(山豆根))
Sophora tetraptera[-]()
Sophora tomentosa L.[-]()

분 자 식 

C₁₅H₂₀N₂O

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

244.339

녹 는 점 

pale yell. oily°C

생리학적효과 

Antiarrhythmic, diuretic, purgative agent. Cardiotonic agent inducing tachycardia. Major toxic alkaloid responsible for [crooked calf disease] caused by leguminous plants. Toxicity: Exp. teratogen.

굴 절 율 

[α]20 D = -166° (C 1.12,EtOH)

UV_CHART 

(λmax, nm) (EtOH):309(8000), 233(6800)

CNMR_CHART 

(CDCl3) δ: 104.3(C1), 138.6(C2), 116.6(C3), 163.5(C4), 51.6(C6), 32.7(C7), 22.6(C8), 35.6(C9), 151.1(C10), 63.3(C11), 25.7(C12), 19.2(C13), 20.5(C14), 53.0(C15), 54.4(C17)

MASS_CHART 

GCM+= 244, m/z= 243, 229, 160, 146, 136, 122, 98(100), 97, 41

참고문헌 

· S. Okuda et al., Chem. Pharm. Bull., 13, 482, 1965(uv,ir) · HM. Fales et al., J. Am. Chem. Soc., 92, 1590, 1970(ms) · F. Bohlmann et al., Chem. Ber., 108, 1043, 1975(cmr) · JF. Couch, J. Am. Chem. Soc., 61, 3327, 1939 · I. Ribas et al., An. R. Soc. Esp. Fis. Quim., Ser. B, 48, 161, 167, 1952 · EE. van Tamelen et al., J. Am. Chem. Soc., 80, 4659, 1958 · SI. Goldberg et al., J. Org. Chem., 37, 1823, 1972 · RF. Keeler et al., CA, 85, 138290f, 1976(tox) · JM. Lobo et al., An. Quim., 73, 1366, 1977 · Atta-ur-Rahman et al., J. Nat. Prod., 54, 929, 1991 · DS. Rycroft et al., Magn. Reson. Chem., 29, 936, 1991(nmr) · DJ. Robins et al., Magn. Reson. Chem., 30, 1125, 1992