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▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
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성 분 명 |
alpha-Allocryptopine |
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다른이름들 |
beta-Homochelidonine
5,7,8,15-Tetrahydro-3,4-dimethoxy-6-methylbenzo[e][1,3]dioxolo[4,5-k][3]-benzazecin-14(6H)-one
Allocryptopine
Fagarine I
alpha-Fagarine
gamma-Homochelidonine
Thalictrimine |
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함유 천연물 |
Caltha palustris L. var. palustris[동의나물(Dong-ui-na-mul)](마제초(馬蹄草))
Chelidonium majus L.[]()
Corydalis ternata Nakai[들현호색(Deul-hyeon-ho-saek)](현호색(玄胡索))
Corydalis turtschaninovii Fa yanjusuo[]()
Hordeum vulgare var. hexastichon (L.) Asch.[보리(Bo-ri)](맥아(麥芽)) |
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분 자 식 |
C21H23NO5 |
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화학족 분류 |
알칼로이드(alkaloid); |
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분 자 량 |
369.421 |
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녹 는 점 |
160-161(anhyd.)°C EtOH/Et2O |
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생리학적효과 |
Hypotensive agent, cardiac inhibitor, respiratory stimulant, muscle relaxant. |
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UV_CHART |
(λmax, nm) (EtOH):230(4.1), 285(3.8) |
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HNMR_CHART |
(CDCl3) δ:6.95(s, H1), 6.64(s, H4), 2.86(m, H5), 2.60(m, H6), 3.5-4.0(m, H8,13), 6.87(q, 8.5, H11,12), 1.85(3H, s, NMe), 3.79(3H, s, OMe), 3.84(3H, s, OMe), 5.92(s, methylene dioxy) |
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CNMR_CHART |
(5% C6D6 in CDCl3) δ: 82.15, 119.13, 121.11, 83.44, 109.22, 5.43, 30.74, 23.39, 101.78, 124.71, 120.65, 83.88, 100.82, 102.80, 19.46, 166.37, 105.92, 14.23, 28.71, 33.67, 74.22 |
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MASS_CHART |
M+= 369, m/z= 354, 352, 341, 338, 326, 325, 311, 297, 283, 268, 267, 206, 164(base), 163, 149, 134 |
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참고문헌 |
· H. Guinaudeau et al., J. Nat. Prod., 45, 237, 1982
· LF. Han et al., J. Chromatogr., 543, 1, 123, 1991
· Redemann et al., J. Am. Chem. Soc., 71, 1030, 1949(uv)
· K. Awasa et al., J. Org. Chem., 47, 4275, 1982(pmr,cmr)
· RD. Haworth et al., J. Chem. Soc., 445, 1926
· V. Deulofeu et al., J. Org. Chem., 12, 217, 1947
· L. Dolejs et al., Coll. Czech. Chem. Comm., 29, 2479, 1964(ms)
· JCN. Ma et al., Can. J. Chem., 43, 1849, 1965(pmr)
· L. Hruban et al., Coll. Czech. Chem. Comm., 32, 3414, 1967(uv)
· S. Teitel et al., Helv. Chim. Acta, 56, 553, 1973
· TT. Nakashima et al., Org. Magn. Reson., 5, 9, 1973(cmr)
· AR. Battersby et al., J. Chem. Soc. Perkin Trans. 1, 1147, 1975
· M. Hanaoka et al., Heterocycles, 4, 1685, 1976
· T. Sakai et al., Acta Cryst. C, 44, 838, 1988
· DE. Raynie et al., Biochem. Syst. Ecol., 18, 45, 1990 |
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