코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Allyl isothiocyanate

다른이름들 

3-Isothiocyanato-1-propene Allyl mustard oil Mustard oil Prop-2-enyl isothiocyanate Prop-2-enyl-isothio-cyanate

함유 천연물 

Brassica chinensis L.[](백채(白菜))
Brassica juncea (L.) Czern. var. juncea[갓(Gat)](개채(芥菜))
Brassica juncea var. crispifolia L.H.Bailey[겨자(Gyeo-ja)](백개자(白芥子))
Brassica oleracea var. capitata L.[양배추(Yang-bae-chu)]()
Descurainia sophia (L.) Webb ex Prantl[재쑥(Jae-ssuk)](정력자({정}{력}子))
Raphanus sativus L.[무(Mu)](나복자(蘿蔔子),나복(蘿蔔),나복엽(蘿蔔葉),나복근(蘿蔔根),내복자(萊복子))

분 자 식 

C₄H₅NS

화학족 분류 

지방족화합물(aliphatic);

분 자 량 

99.1551

생리학적효과 

Counterirritant. Toxicity: very pungent, irritating odour, highly toxic, mutagen. Irritant and skin allergen. LD50 (rat, orl) 112 mg/kg. LD50 (rbt, skn) 88 mg/kg. LD50 orally in rats: 339 mg/kg (Jenner). Exp. reprod. and teratogenic effects. Goitrogenic (antithyroid) activity. LDLo(mus, ipr) 4mg/kg.

굴 절 율 

[α]20 D = +52.1°

HNMR_CHART 

(CCl4) δ:4.18(H alpha)

참고문헌 

· A. Mathias, Tetrahedron, 21, 1073, 1965(pmr) · A. Kjaer et al., Acta Chem. Scand., 7, 1267, 1953; 17, 2143, 1963(ms) · RA. Cole et al., Phytochemistry, 14, 2293, 1975 · Aldrich Library of FT-IR Spectra, 1st edn., 1, 875A (ir) · B. Tollens et al., Annalen, 156, 134, 1870 · ME. Daxenbichler et al., J. Agric. Food Chem., 12, 127, 1964 · P. Langer et al., Endocrinology (Baltimore), 76, 151, 1965 · Food Chemicals Codex, 2nd Ed., 31, 1972 · T. Yanemoto et al., J. Magn. Reson., 13, 153, 1974 · M. Mahuja et al., Indian J. Chem., 11, 15, 1976 · T. Yamamoto et al., Org. Prep. Proced. Int., 26, 555, 1994(pmr)