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▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
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성 분 명 |
Acutumine |
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함유 천연물 |
Menispermum dauricum DC.[새모래덩굴(Sae-mo-rae-deong-gul)](편복갈근(편복葛根),편복갈(편복葛))
Sinomenium acutum (Thunb.) Rehder & E.H.Wilson[방기(Bang-gi)](방기(防己)) |
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분 자 식 |
C19H24ClNO6 |
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화학족 분류 |
알칼로이드(alkaloid); |
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분 자 량 |
397.859 |
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녹 는 점 |
236-238(dec.)°C |
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굴 절 율 |
[α]15 D = -206° (C 0.69,pyridine) |
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UV_CHART |
(λmax, nm) (EtOH):245, 270 |
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HNMR_CHART |
(C5D5N,400 MHz) δ:5.00(1H, s, H1), 5.58(1H, s, H3), 2.50(1H, d, 15, H5), 3.02(1H, d, 15, H5), 2.64(1H, dd, 7, 12, H9), 3.14(1H, dd, 12, 12, H9), 5.16(1H, dd, 7, 12, H10), 1.61(1H, m, H14), 2.65(1H, m, H14), 2.43(1H, m, H15), 2.65(1H, m, H15), 2.38(3H, s, H16), 3.71(3H, s, H17), 3.78(3H, s, H18), 4.03(3H, s, H19) |
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CNMR_CHART |
(C5D5N,100 MHz) δ: 70.7(C1), 189.0(C2), 105.6(C3), 201.4(C4), 47.3(C5), 192.9(C6), 139.0(C7), 159.8(C8), 41.5(C9), 57.9(C10), 68.4(C11), 53.3(C12), 73.0(C13), 38.6(C14), 51.8(C15), 36.4(C16), 58.9(C17), 60.2(C18), 60.5(C19) |
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MASS_CHART |
M+= 397, m/z= 362, 334, 209(100), 194, 181, 166, 150, 399(isotope paek) |
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참고문헌 |
· M. Tomita et al., Yakugaku Zasshi, 90, 1182, 1970(uv,ir)
· Y. Sugimoto et al., Phytochemistry, 49, 1293, 1998(nmr)
· M. Tomita et al., Tetrahedron Lett., 25, 2421, 1967
· K. Goto et al., Bull. Chem. Soc. Jpn., 4, 220, 1929
· Y. Nagai et al., Tetrahedron Lett., 24, 1933, 1969(ms)
· T. Tomita et al., Chem. Pharm. Bull., 19, 770, 1971(uv,ir,pmr) |
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