코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

6-Hydroxyhyoscyamine; (-)-form

다른이름들 

Alkaloid V Anisodamine alpha-(Hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

함유 천연물 

Atropa belladonna L.[벨라도나](전가초(顚茄草))
Datura inoxia Mill.[-]()
Physochlaina dubia[-]()
Zizyphus jujuba Mill. var. jujuba[묏대추나무(Moet-dae-chu-na-mu)](산조인(酸棗仁))

분 자 식 

C₁₇H₂₃NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

305.377

녹 는 점 

61-62°C C6H6

생리학적효과 

Anticholinergic, antispasmodic agent. Reduces effects of acute myocardial infarction in rabbits. Atropine-like activity.

굴 절 율 

[α]20 D = -13.5° (C 1.9,MeOH)

참고문헌 

· L. Witte et al., Planta Med., 5, 390, 1986 · PT. Mirzamatov et al., Khim. Prir. Soedin., 493, 1972; 416, 540, 1974(pmr,ms) · G. Fodor et al., Arch. Pharm. (Weinheim, Ger.), 295, 91, 1962 · A. Romeike, Naturwissenschaften, 49, 281, 1962 · PK. Hsiao et al., CA, 95, 138447u, 1981 · J. Shi et al., CA, 100, 114755p, 1984