|
|
 |
▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
|
|
|
성 분 명 |
(+)-5-alpha,9-alpha-Dihydroxymatrine |
|
|
|
다른이름들 |
5,9-Dihydroxymatridin-15-one ((+)-form)
Sophoranol ((+)-form); 9alpha-Hydroxy
Sofranol; 9alpha-Hydroxy
5-Hydroxymatrine; 9alpha-Hydroxy
5-alpha-Hydroxymatrine ((+)-form); 9alpha-Hydroxy |
|
함유 천연물 |
Sophora flavescens Solander ex Aiton[고삼(Go-sam)](고삼(苦蔘),고삼실(苦蔘實),수괴(水槐),지괴(地槐)) |
|
분 자 식 |
C15H24N2O3 |
|
화학족 분류 |
알칼로이드(alkaloid); |
|
분 자 량 |
280.37 |
|
녹 는 점 |
192-193°C Me2CO |
|
굴 절 율 |
[α]20 D = +40.6° (C 0.17,EtOH) |
|
HNMR_CHART |
(CDCl3,100 MHz) δ:4.31(1H, dd, 13.5, 1, H17 eq.), 3.79(1H, m, H11), 3.67(1H, m, H9), 3.17(1H, d, 13.5, H17 ax.), 3.05(1H, br dd, 10, 4, H10 eq.), 2.78(1H, br d, 10, H2 eq.) |
|
CNMR_CHART |
(CDCl3,25 MHz) δ: 56.3, 22.5, 36.9, 68.0, 37.2, 38.4, 35.0, 62.7, 34.0, 53.8, 26.8, 18.6, 32.6, 171.2, 46.5 |
|
MASS_CHART |
M+= 280, m/z= 263, 221, 112, 55(100) |
|
참고문헌 |
· S. Ohmiya et al., Phytochemistry, 18, 645, 1979(ir,pmr,cmr,ms)
· F. Bohlmann et al., Chem. Ber., 91, 2189, 1958
· S. Okuda et al., Chem. Pharm. Bull., 13, 482, 1965
· S. Ohmiya et al., Phytochemistry, 18, 648, 1978
· I. Murakoshi et al., Phytochemistry, 21, 2379, 1982 |
|
|
|
|
|
