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▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
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성 분 명 |
Sophoranol ((+)-form) |
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다른이름들 |
Sofranol
5-Hydroxymatrine
5-alpha-Hydroxymatrine ((+)-form) |
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함유 천연물 |
Sophora flavescens Solander ex Aiton[고삼(Go-sam)](고삼(苦蔘),고삼실(苦蔘實),수괴(水槐),지괴(地槐))
Sophora macrocarpa[-]() |
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분 자 식 |
C15H24N2O2 |
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화학족 분류 |
알칼로이드(alkaloid); |
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분 자 량 |
264.371 |
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녹 는 점 |
171°C |
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생리학적효과 |
CNS depressant effect, sedative, hypnotic, anticonvulsion properties & no analgesic effect. |
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굴 절 율 |
[α]20 D = +66°( H2O) |
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HNMR_CHART |
(CDCl3,100 MHz) δ:4.34(dd, H17 eq.), 3.21(d, H17 ax.), 3.77(m, H11), 2.75(br d, H2 eq.), 2.86(br d, H10 eq.) |
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CNMR_CHART |
(CDCl3) δ: 56.6(C2), 20.4(C3), 36.5(C4), 67.7(C5), 68.5(C6), 36.8(C7), 26.0(C8), 22.5(C9), 56.9(C10), 53.1(C11), 26.7(C12), 18.8(C13), 32.7(C14), 46.5(C17) |
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MASS_CHART |
EIM+= 264.184, m/z= 263, 247, 246, 222, 221, 208, 166, 112, 112, 98, 96 |
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참고문헌 |
· F. Bohlmann et al., Chem. Ber., 108, 1043, 1975(cmr)
· A. Ueno et al., Chem. Pharm. Bull., 26, 1832, 1978
· S. Okuda et al., Chem. Pharm. Bull., 13, 482, 1965
· S. Ohmiya et al., Phytochemistry, 18, 645, 1979(pmr)
· F. Bohlmann et al., Chem. Ber., 91, 2189, 1958
· AM. Abdel-Baky et al., Fitoterapia, 58, 5, 295, 1987
· S. Ohmiya et al., Chem. Pharm. Bull., 28, 546, 1980 |
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