코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Sophocarpine ((-)-form)

다른이름들 

13,14-Didehydromatridin-15-one

함유 천연물 

Sophora alopecuroides L.[-]()
Sophora flavescens Solander ex Aiton[고삼(Go-sam)](고삼(苦蔘),고삼실(苦蔘實),수괴(水槐),지괴(地槐))
Sophora japonica L.[회화나무(Hoe-hwa-na-mu)](괴화(槐花),괴각(槐角),괴지(槐枝),괴엽(槐葉),괴각자(槐角子),괴교(槐膠),괴근백피(槐根白皮),괴백피(槐白皮),괴실(槐實),괴윤(槐潤),괴자(槐子),괴자인(槐子仁),괴조(槐條),수궁괴(守宮槐))
Sophora moorcroftiana (Wall.) Benth.ex Bak.[-]()
Sophora pachycarpa[-]()
Sophora prodanii[-]()
Sophora subprostrata Chun et T. Chen[광두근](산두근(山豆根))
Sophora viciifolia Hance[-]()

분 자 식 

C₁₅H₂₂N₂O

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

246.355

녹 는 점 

53-54°C

생리학적효과 

Antineoplastic agent, inhibitor of Walker 256 carcinosarcoma and other tumours. Antiarrhythmic agent, nematocide. Toxicity: LD50 (rat, orl) 196 mg/kg. LD50 (rat, ipr) 124 mg/kg.

굴 절 율 

[α]D = -29.4°(EtOH)

UV_CHART 

(λmax, nm) (EtOH):260(2500)

참고문헌 

· S. Okuda et al., Chem. Pharm. Bull., 13, 482, 1965(uv,ir) · AP. Orekhov et al., Ber., 67, 77, 1934 · S. Okuda et al., Chem. Ind. (London), 1326, 1962 · S. Iskandarov et al., Khim. Prir. Soedin., 4, 106, 1968; Chem. Nat. Compd. (Engl. Transl.), 4, 90, 1968(ms) · UN. Zainutdinov et al., CA, 72, 121754u, 1970 · TK. Yunusov et al., Khim. Prir. Soedin., 8, 200, 1972; Chem. Nat. Compd. (Engl. Transl.), 8, 201, 1972(ir) · JK. Kushmuradov et al., Phytochemistry, 11, 3441, 1972 · SA. Karakozova et al., Khim. Prir. Soedin., 11, 664, 1975; Chem. Nat. Compd. (Engl. Transl.), 11, 703, 1975 · S. Kuchkarov et al., Khim. Prir. Soedin., 13, 541, 1977; Chem. Nat. Compd. (Engl. Transl.), 13, 451, 1977 · BA. Abdusalamov et al., Khim. Prir. Soedin., 13, 549, 1977; Chem. Nat. Compd. (Engl. Transl.), 13, 458, 1977 · A. Ueno et al., Chem. Pharm. Bull., 26, 1832, 1978 · K. Morinaga et al., Chem. Pharm. Bull., 26, 2483, 1978 · Yuk. Kushmuradov et al., Khim. Prir. Soedin., 14, 231, 1978; Chem. Nat. Compd. (Engl. Transl.), 14, 190, 1978 · YL. Wang et al., J. Tradit. Chin. Med., 7, 35, 1987 · K. Saito et al., J. Chromatogr., 462, 333, 1989 · K. Saito et al., Planta Med., 56, 487, 1990 · K. Matsuda et al., J. Agric. Food Chem., 39, 189, 1991