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▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
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성 분 명 |
Senkyunolide H |
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다른이름들 |
(E)-(6RS,7SR)-3-Butylidene-4,5-dihydro-6,7-dihydroxyphthalide
Ligustilide; 6,7-Dihydro, 6S,7R-Dihydroxy
3-Butylidene-4,5-dihydro-1(3H)-isobenzofuranone; 6,7-Dihydro, 6S,7R-Dihydroxy
3-Butylidene-4,5-dihydrophthalide; 6,7-Dihydro, 6S,7R-Dihydroxy |
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함유 천연물 |
Cnidium officinale Makino[천궁(Cheon-gung)](천궁(川芎),강리(江籬),궁궁(芎궁),무궁(撫芎),작뇌궁(雀腦芎))
Ligusticum chuanxiong Hort.[](궁궁(芎궁))
Ligusticum wallichii Franchet[-](궁궁(芎궁)) |
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분 자 식 |
C12H16O4 |
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화학족 분류 |
알파-피론(alpha_pyrone); |
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분 자 량 |
224.259 |
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녹 는 점 |
92-23°C |
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굴 절 율 |
[α]D = 0°(C 1.07, CHCl3) |
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UV_CHART |
(λmax, nm) (EtOH):274 |
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HNMR_CHART |
(CDCl3,500 MHz) δ:2.36-2.42(1H, m, H4), 2.62-2.69(1H, m, H4), 1.79-1.85(1H, m, H5), 2.10-2.17(1H, m, H5), 4.06(1H, ddd, 7.9, 3.9, 2.5, H7), 4.61(1H, d, 3.9, H6), 5.31(1H, t, 7.9, H8), 2.36(2H, dt, 7.9, 7.4, H9), 1.50(2H, tq, 7.4, 7.4, H10), 0.95(3H, t, 7.4, H11) |
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CNMR_CHART |
(CDCl3,125 MHz) δ: 169.4, 153.4, 148.2, 18.5, 25.6, 67.5, 63.3, 125.5, 114.5, 28.1, 22.3, 13.8 |
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MASS_CHART |
M+= 224, m/z= 180(100), 175, 151 |
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참고문헌 |
· T. Naito et al., Phytochemistry, 31, 2, 639, 1992
· K. Kaneko et al., Chem. Pharm. Bull., 35, 11, 4460, 1987(ms)
· E. Stahl et al., Naturwissenschaften, 54, 118, 1967
· GK. Nikonov et al., Khim. Prir. Soedin., 7, 387, 1971; Chem. Nat. Compd. (Engl. Transl.), 373, 1971
· T. Yamagishi et al., Yakugaku Zasshi, 97, 237, 1977
· W. Pushan et al., Phytochemistry, 23, 2033, 1984
· M. Kobayashi et al., Chem. Pharm. Bull., 35, 4789, 1987
· M. Kaouadjii et al., J. Nat. Prod., 49, 872, 1986
· S. Li et al., Synth. Commun., 23, 2061, 2909, 1993
· JN. Grech et al., J. Nat. Prod., 57, 1682, 1994
· JJ. Beck et al., J. Nat. Prod., 58, 1047, 1995
· Y. Ogawa et al., Synlett, 871, 1995 |
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