코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Senkyunolide F

다른이름들 

9-Hydroxyligustilide 3-Butylidene-4,5-dihydro-1(3H)-isobenzofuranone; 9-Hydroxy 3-Butylidene-4,5-dihydrophthalide; 9-Hydroxy

함유 천연물 

Cnidium officinale Makino[천궁(Cheon-gung)](천궁(川芎),강리(江籬),궁궁(芎궁),무궁(撫芎),작뇌궁(雀腦芎))
Ligusticum chuanxiong Hort.[](궁궁(芎궁))

분 자 식 

C₁₂H₁₄O₃

화학족 분류 

알파-피론(alpha_pyrone);

분 자 량 

206.244

녹 는 점 

oily°C

굴 절 율 

[α]D = 0°(C 1.89, CHCl3)

UV_CHART 

(λmax, nm) (EtOH):283(6300), 296(6100), 323(7300)

HNMR_CHART 

(CDCl3,200 MHz) δ:0.97(3H,t,7.3,H11), 4.74(1H,dt,8.3,6.4,H9), 5.23(1H,d,8.3,H8), 6.06(1H,dt,9.3,3.9,H6), 6.29(1H,dt,9.8,2.0,H7)

MASS_CHART 

M+= 206, m/z= 188, 177(100), 150, 147, 132, 149

참고문헌 

· T. Naito et al., Phytochemistry, 31, 2, 639, 1992 · M. Fujita et al., Chem. Pharm. Bull., 32, 9, 3770, 1984; 35, 4, 1427, 1987(uv,ir,pmr,ms) · E. Stahl et al., Naturwissenschaften, 54, 118, 1967 · GK. Nikonov et al., Khim. Prir. Soedin., 7, 387, 1971; Chem. Nat. Compd. (Engl. Transl.), 373, 1971 · T. Yamagishi et al., Yakugaku Zasshi, 97, 237, 1977 · W. Pushan et al., Phytochemistry, 23, 2033, 1984 · M. Kobayashi et al., Chem. Pharm. Bull., 35, 4789, 1987 · M. Kaouadjii et al., J. Nat. Prod., 49, 872, 1986 · T. Tsuchida et al., Chem. Pharm. Bull., 35, 4460, 1987 · S. Li et al., Synth. Commun., 23, 2061, 2909, 1993 · JN. Grech et al., J. Nat. Prod., 57, 1682, 1994 · JJ. Beck et al., J. Nat. Prod., 58, 1047, 1995 · Y. Ogawa et al., Synlett, 871, 1995