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 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Senkyunolide D

다른이름들 

4,5-Dihydro-3-hydroxy-3-(1-oxobutyl)-1(3H)-isobenzofuranone Senkyunolide A; 3-Hydroxy, 8-Oxo 3-Butyl-4,5-dihydro-1(3H)-isobenzofuranone; 3-Hydroxy, 8-Oxo Sedanenolide; 3-Hydroxy, 8-Oxo Senkyunolide; 3-Hydroxy, 8-Oxo 3-Butyl-4,5-dihydrophthalide; 3-Hydroxy, 8-Oxo

함유 천연물 

Cnidium officinale Makino[천궁(Cheon-gung)](천궁(川芎),강리(江籬),궁궁(芎궁),무궁(撫芎),작뇌궁(雀腦芎))
Ligusticum chuanxiong Hort.[](궁궁(芎궁))

분 자 식 

C₁₂H₁₄O₄

화학족 분류 

알파-피론(alpha_pyrone);

분 자 량 

222.243

녹 는 점 

oily°C

굴 절 율 

[α]D = 0°(C 1.43, CHCl3)

UV_CHART 

(λmax, nm) (EtOH):287(2600), 326(sh. 2250)

HNMR_CHART 

(CDCl3,200 MHz) δ:0.92(3H,t,7.3,H11), 1.67(2H,sext,7.3,H10), 2.28(1H,dt,18.1,7.3,H9a), 2.65(1H,dt,18.1,6.8,H9b), 6.09(1H,dt,9.8,4.0,H6), 6.27(1H,dt,9.8,2.0,H7)

MASS_CHART 

M+= 222, m/z= 204, 134(100), 106, 79, 77, 71

참고문헌 

· T. Naito et al., Phytochemistry, 31, 2, 639, 1992 · M. Fujita et al., Chem. Pharm. Bull., 32, 9, 3770, 1984; 35, 4, 1427, 1987(uv,ir,pmr,ms) · LF. Bjeldanes et al., J. Org. Chem., 42, 2333, 1977 · T. Yamagishi et al., Yakugaku Zasshi, 97, 237, 1977; CA, 87, 44123t