코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Salutaridine; (+)-form

다른이름들 

Floripavine; (+)-form Sinoacutine; (+)-form Salutarine; (+)-form

함유 천연물 

Papaver somniferum L.[양귀비(Yang-gwi-bi)](앵속각(罌粟殼))

분 자 식 

C₁₉H₂₁NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

327.384

녹 는 점 

197-198°C EtOAc

생리학적효과 

Intermediate in biosynth. of morphine alkaloids. Shows antitumour activity vs. Walker 256 carcinosarcoma.

굴 절 율 

[α]D = +111°(C 1.69, EtOH)

UV_CHART 

(λmax, nm) (MeOH):236(4.25), 279(3.78)

HNMR_CHART 

(CDCl3) δ:7.55(3H, s, NMe), 6.26(3H, s, OMe), 6.12(3H, s, OMe), 3.32(1H, H1 or 2), 3.28(1H, H2 or 1), 2.44(1H, H5), 3.68(1H, H8)

MASS_CHART 

M+= 327, m/z= 326, 312, 299, 284

참고문헌 

· DHR. Baeton, J. Chem. Soc., 2423, 1965(ir,pmr) · DMS. Wheeler et al., J. Am. Chem. Soc., 89, 4494, 1967(ms) · AI. Gray et al., Planta Med., 41, 2, 1, 1981(uv,ms) · C. Chambers et al., Chem. Comm., 449, 1966 · T. Kametani et al., J. Chem. Soc.(C), 2030, 1969 · A. Shafiee et al., J. Pharm. Sci., 64, 1570, 1975 · RA. Barnes et al., Phytochemistry, 20, 543, 1981 · G. Sariyar et al., Planta Med., 58, 368, 1992