코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Reticuline (S-form, (+)-form)

다른이름들 

Coclanoline Laudanosoline 4',6-dimethyl ether (S)-1-(3-Hydroxy-4-methoxybenzyl)-2-methyl-6-methoxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline

함유 천연물 

Lindera strychinifolia (Sieb. et Zucc.) F. Vill.[오약](오약(烏藥),천태오약(天台烏藥))
Magnolia obovata Thunb.[일본목련(Il-bon-mong-nyeon)](후박(厚朴))
Magnolia salicifolia (Siebold & Zucc.) Maxim.[살리시폴리아 목련]()
Papaver somniferum L.[양귀비(Yang-gwi-bi)](앵속각(罌粟殼))

분 자 식 

C₁₉H₂₃NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

329.4

녹 는 점 

amorphous°C

생리학적효과 

Intermediate in the biosynth. of Morphine

굴 절 율 

[α]25 D = +100° (C 0.78,MeOH)

UV_CHART 

(λmax, nm) :283(3.90)

HNMR_CHART 

(CDCl3,60 MHz) δ:2.5(3H, s, NMe), 3.8(6H, s, 2xOMe), 5.7(2H, s, 2xOH)

MASS_CHART 

m/z= 330[M+H], 193(100), 137

참고문헌 

· M. Konda et al., Chem. Pharm. Bull., 23, 1063, 1975(ir,pmr) · J. Comin et al., Alkaloids, 419, 1968 · JL. Beal et al., J. Nat. Prod., 40, 593, 1977(uv,ms) · I. Kimura et al., Planta Med., 48, 1, 43, 1983(pmr,ms) · G. Billek, Monatsh. Chem., 87, 106, 1956 · KW. Gopinath et al., Chem. Ber., 92, 1657, 1959 · AR. Battersby et al., J. Chem. Soc., 3323, 1965 · DS. Bhakuni et al., J. Chem. Soc. Perkin 1, 1662, 1977 · R. Hirsenkorn, Tetrahedron Lett., 31, 7591, 1990