코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Palmatine

다른이름들 

Berbericinine 5,6-Dihydro-2,3,9,10-tetramethoxybenzo[a,g]quinolizinium

함유 천연물 

Berberis soulieana[-]()
Coptis chinensis Franch.[](황련(黃連))
Coptis deltoidea C. Y. Cheng et Hsiao[](황련(黃連))
Coptis japonica (Thunb.) Makino[황련(Hwangn-yeon)](황련(黃連))
Coptis teeta[]()
Corydalis turtschaninovii Fa yanjusuo[]()
Corydalis yanhusuo W. T. Wang[](연호색(延胡索))
Nandina domestica Thunb.[남천(Nam-cheon)](남천죽자(南天竹子),남천죽엽(南天竹葉),남천죽근(南天竹根))
Phellodendron amurense Rupr.[황벽나무(Hwang-byeok-na-mu)](황백(黃柏))
Phellodendron chinense Schneid.[](황백(黃柏),황벽(黃蘗))

분 자 식 

C₂₁H₂₂NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

352.414

생리학적효과 

Uterine contractant. Bactericidal activity. Produces antiarrhythmic, inotropic, adrenocorticotropic, anticholinesterase and analgesic effects in expl. animals.

HNMR_CHART 

(TFA,100 MHz) δ:(as chloride); 7.63(1H, s, H1), 7.06(1H, s, H4), 9.58(1H, s, H8), 8.08(1H, d, 9, H11), 7.96(1H, d, 9, H12), 8.52(1H, s, H13), 4.12(3H, s, 2-OMe), 4.06(3H, s, 3-OMe), 4.31(3H, s, 9-OMe), 4.18(3H, s, 10-OMe)

참고문헌 

· A. Ikuta et al., Phytochemistry, 27, 7, 2143, 1988 · MP. Cava et al., J. Nat. Prod., 28, 73, 1965 · K. Jewers et al., J. Chem. Soc. Perkin Trans. 2, 1393, 1972(cmr) · JL. Beal et al., Lloydia, 39, 65, 1976; 39, 204, 1976(uv,ir) · E. Spath et al., Ber., 58, 2267, 1925 · RD. Haworth et al., J. Chem. Soc., 546, 1927 · AR. Skerl et al., Phytochemistry, 10, 2719, 1971 · S. Pavelka et al., Coll. Czech. Chem. Comm., 41, 3157, 1976 (uv) · RA. Hussain et al., Heterocycles, 29, 2257, 1989(nmr)