코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Nortrilobine

다른이름들 

N-Demethyltrilobine

함유 천연물 

Cocculus trilobus (Thunb.) DC.[댕댕이덩굴(Daeng-daeng-i-deong-gul)](목방기(木防己),방기(防己))

분 자 식 

C₃₄H₃₂N₂O₅

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

548.644

녹 는 점 

177-180°C MeOH

굴 절 율 

[α]25 D = +216° (C 0.44,CHCl3)

UV_CHART 

(λmax, nm) (MeOH):218(4.60), 237(4.62), 275(3.66), 287(3.68), 300 sh(3.53)

HNMR_CHART 

(CDCl3,60 MHz) δ:3.78(3H, s, OMe), 3.92(3H, s, OMe), 6.21-7.4(10H, m, H-aromatic)

MASS_CHART 

EIM+= 548, m/z= 335, 322, 321(100), 307, 211, 161

참고문헌 

· MA. El-Kawi et al., J. Nat. Prod., 47, 459, 1984(uv,ir,pmr,ms) · H. Kondo et al., Yakugaku Zasshi, 532, 465, 1926; 542, 265, 1927 · M. Tomita et al., Pharm. Bull., 1, 1, 1953 · M. Tomita et al., Yakugaku Zasshi, 83, 190, 1963 · Y. Inubushi et al., Yakugaku Zasshi, 83, 288, 1963 · J. Baldas et al., J. Chem. Soc. Perkin Trans. 1, 592, 1972 · IRC. Bick et al., J. Chem. Soc. Perkin Trans. 1, 2884, 1972 · VJ. Tripathi et al., Indian J. Chem., Sect. B, 14, 62, 1976 · Y. Inubushi et al., Chem. Pharm. Bull., 25, 1636, 1977 · S. Dasgupta et al., J. Nat. Prod., 42, 399, 1979