코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Norsanguinarine

다른이름들 

[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine 2,3;7,8-Bis(methylenedioxy)benzo[c]phenanthridine

함유 천연물 

Chelidonium majus L.[]()
Papaver somniferum L.[양귀비(Yang-gwi-bi)](앵속각(罌粟殼))

분 자 식 

C₁₉H₁₁NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

317.304

녹 는 점 

pale-yell. 285-287°C CHCl3/MeOH

UV_CHART 

(λmax, nm) (EtOH):212(4.33), 243(4.67), 251 sh.(4.50), 275 sh.(4.50), 281(4.55), 293 sh.(4.41), 328(4.22), 341(4.00), 3.82(3.60), 399(3.65)

HNMR_CHART 

(TFA-d,60 MHz) δ:7.94(1H, s, H1), 7.42(1H, s, H4), 8.47(1H, d, 10, H5), 8.15(1H. d, 10, H6), 9.51(1H, s, H8), 7.92(1H. d, 8, H11), 8.45(1H, d, 8, H12), 6.25(2H, s, OCH2O), 6.50(2H, s, OCH2O)

MASS_CHART 

M+= 317, m/z= 261, 260, 259, 204, 203, 202, 201, 175, 101(100)

참고문헌 

· T. Furuya et al., Phytochemistry, 11, 3041, 1972(uv,ir,pmr,ms) · BD. Krane et al., J. Nat. Prod., 47, 1, 1984(uv,ir,pmr,ms) · K. Haisova et al., Coll. Czech. Chem. Comm., 38, 3312, 1973 · A. Ikuta et al., Phytochemistry, 13, 2175, 1974 · K. Haisova et al., Coll. Czech. Chem. Comm., 40, 1576, 1975 · A. Ikuta et al., Phytochemistry, 15, 577, 1976 · W. Dopke et al., Z. Chem., 16, 54, 1976 · H. Itokawa et al., Phytochemistry, 17, 839, 1978 · L. Castedo et al., Tetrahedron Lett., 2923, 1978 · B. Sener et al., Phytochemistry, 22, 2073, 1983