코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Methylephedrine ((-)-form)

다른이름들 

N-Methylephedrine 2-Dimethylamino-1-phenyl-1-propanol (1R,2S-form)

함유 천연물 

Ephedra equisetina Bunge[목적마황](마황(麻黃),마황근(麻黃根))
Ephedra intermedia Schrenk et C. A. Mey[](마황(麻黃))
Ephedra sinica Stapf[초마황](마황(麻黃),마황근(麻黃根))

분 자 식 

C₁₁H₁₇NO

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

179.264

녹 는 점 

87-88°C MeOH

생리학적효과 

Analeptic.

굴 절 율 

[α]D = -29.2°(MeOH)

CNMR_CHART 

(D2O,25.15 MHz) δ: (as HCl salt): 8.5, 67.4, 71.5, 41.1, 42.8, 140.3, 126.8, 129.8, 129.3

참고문헌 

· Y. Sakai et al., Gifu-Kien Eisei Kenkyushoho, 36, 30, 1991; CA, 116, 262604, J · T. Misaki et al., Chem. Pharm. Bull., 31, 7, 2359, 1983 · K. Fujita et al., Chem. Pharm. Bull., 27, 1, 43, 1979(cmr) · S. Smith, J. Chem. Soc., 2056, 1927 · WN. Nagai et al., Annalen, 470, 157, 1929 · W. Leithe, Ber., 65, 660, 1932 · TA. Smith, Phytochemistry, 16, 9, 1977 · T. Shono et al., Tetrahedron Lett., 24, 4577, 1983 · J. Blagg et al., Chem. Comm., 653, 1985 · S. Miyano et al., J. Org. Chem., 50, 4350, 1985