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▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
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성 분 명 |
Mamanine ((+)-form) |
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다른이름들 |
6-[Octahydro-1-(hydroxymethyl)-2H-quinolizin-3-yl]-2(1H)pyridinone |
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함유 천연물 |
Sophora flavescens Solander ex Aiton[고삼(Go-sam)](고삼(苦蔘),고삼실(苦蔘實),수괴(水槐),지괴(地槐)) |
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분 자 식 |
C15H22N2O2 |
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화학족 분류 |
알칼로이드(alkaloid); |
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분 자 량 |
262.355 |
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녹 는 점 |
170-172°C |
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굴 절 율 |
[α]D = +31.7°(C 2.32, EtOH) |
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UV_CHART |
(λmax, nm) (MeOH):233(3.86), 308(3.84), (MeOH,H+): 219, 289 |
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HNMR_CHART |
(DMSO-d6) δ:1.0-1.95(8H,complex m), 1.95-2.27(4H,m), 2.74(4H,bdm), 2.81(1H,bdm), 3.40(large,incl. H2O), 4.42(1H,bds), 6.00(1H,dd,1.7), 6.15(1H,dd,1.9), 7.35(1H,dd,7.9), 11.53(bd,~0.5H) |
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CNMR_CHART |
(DMSO-d6) δ: 163.3, 151.8, 141.1, 116.8, 101.8, 62.9, 62.2, 60.1, 55.9, 43.3, 38.9, 33.5, 29.2, 25.3, 24.2 |
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MASS_CHART |
M+= 262, m/z= 245, 231, 204(100), 127, 124, 122, 121, 84, 83 |
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참고문헌 |
· MM. Kadooka et al., Tetrahedron, 32, 919, 1976
· I. Murakoshi et al., Phytochemistry, 20, 1407, 1981; 21, 2379, 1982; 23, 887, 1984
· K. Saito et al., Chem. Pharm. Bull., 34, 3982, 1986 |
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