코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Magnoflorine

다른이름들 

Corytuberine methosalt Esholine Escholine Thalictrine

함유 천연물 

Aristolochia contorta Bunge[쥐방울덩굴(Jwi-bang-ul-deong-gul)](마두령(馬兜鈴),청목향(靑木香))
Aristolochia debilis Sieb.et Zucc.[](마두령(馬兜鈴))
Caltha palustris L. var. palustris[동의나물(Dong-ui-na-mul)](마제초(馬蹄草))
Chelidonium majus L.[]()
Coptis chinensis Franch.[](황련(黃連))
Coptis japonica (Thunb.) Makino[황련(Hwangn-yeon)](황련(黃連))
Magnolia obovata Thunb.[일본목련(Il-bon-mong-nyeon)](후박(厚朴))
Nandina domestica Thunb.[남천(Nam-cheon)](남천죽자(南天竹子),남천죽엽(南天竹葉),남천죽근(南天竹根))
Phellodendron amurense Rupr.[황벽나무(Hwang-byeok-na-mu)](황백(黃柏))
Phellodendron chinense Schneid.[](황백(黃柏),황벽(黃蘗))
Sinomenium acutum (Thunb.) Rehder & E.H.Wilson[방기(Bang-gi)](방기(防己))
Zanthoxylum piperitum (L.) DC.[초피나무(Cho-pi-na-mu)](화초(花椒),초목(椒目))

분 자 식 

C₂₀H₂₄NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

342.419

녹 는 점 

(as Iodide) 248(dec.)°C

생리학적효과 

Weak curarising and hypotensive agent

굴 절 율 

[α]20 D = +193 (as Iodide)° (C 0.20,MeOH)

UV_CHART 

(λmax, nm) (EtOH):227(4.65), 271(3.93), 310(3.80)

HNMR_CHART 

(DMSO-d6) δ:(as Iodide): 6.90(1H, s, H3), 6.95(2H, s, H8,9), 3.88(3H, s, OMe-10), 3.93(3H, s, OMe-2), 2.98, 3.41(6H, ea. s, NMe)

CNMR_CHART 

(CDCl3/CF3COOD,15 MHz) δ: 140.2, 118.9, 117.7, 148.8, 109.6, 120.3, 23.4, 61.5, 69.7, 30.3, 123.8, 120.8, 110.9, 147.6, 140.2, 119.2, 43.4, 54.2, 55.8, 55.8

MASS_CHART 

EIM+= 342, m/z= 341, 270, 59, 58(100)

참고문헌 

· T. Nakano, Chem. Pharm. Bull., 2, 329, 1954 · HL. Li et al., Lloydia, 33S, 1-286, 1970 · H. Guinaudeau et al., Lloydia, 38, 275, 1975; 42, 437, 1979 · S. Nunome et al., Shoyakugaku Zasshi, 45, 1, 40, 1991(ms) · Collect. Czech. Chem. Commun., 38, 3514, 1973 · D. Butruille et al., Phytochemistry, 13, 680, 1974(uv,ms) · JL. Beal et al., Lloydia, 39, 204, 1976(ir)