코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

(-)-Lupanine

다른이름들 

Hydrorhombinine Tetrahyroanagyrine 2-Oxo-11-alpha-spartein ((-)-form)

함유 천연물 

Sophora exigua[-]()

분 자 식 

C₁₅H₂₄N₂O

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

248.371

녹 는 점 

oily°C

생리학적효과 

Toxicity: LD50 (rat, orl) 1440 mg/kg.

굴 절 율 

[α]D = -61°(Me2CO)

CNMR_CHART 

(CDCl3) δ: 26.7(C1), 19.6(C2), 33.0(C3), 46.6(C6), 32.4(C7), 27.3(C8), 34.9(C9), 61.7(C10), 63.5(C11), 33.5(C12), 24.5(C13), 25.3(C14), 55.3(C15), 52.8(C17)

MASS_CHART 

GCM+= 248, m/z= 247, 150, 149, 136(100), 110, 98, 97, 84, 41

참고문헌 

· K. Saito et al., Phytochemistry, 30, 11, 3793, 1991 · M. Wiewiorowski et al., Can. J. Chem., 45, 1447, 1967(ir,pmr) · F. Bohlmann et al., Chem. Ber., 108, 1043, 1975(cmr) · GR. Clemo et al., J. Chem. Soc., 1811, 1928; 429, 1931 · JF. Couch, J. Am. Chem. Soc., 59, 1469, 1937 · L. Marion, J. Org. Chem., 13, 780, 1948 · L. Marion, Can. J. Chem., 30, 386, 1952 · EE. van Tamelen et al., J. Am. Chem. Soc., 78, 2913, 1956 · GR. Clemo et al., J. Chem. Soc., 3390, 1956 · F. Bohlmann et al., Tetrahedron Lett., 2435, 1965(pmr) · M. Wiewiorowski et al., Can. J. Chem., 45, 1447, 1967(ir,pmr) · HM. Fales et al., J. Am. Chem. Soc., 92, 1590, 1970(ms) · J. Barciszewski et al., Bull. Acad. Pol. Sci., Ser. Sci. Chim., 19, 545, 1971(pmr) · E. Skrzypczak-Jankun et al., Acta Cryst. B, 34, 2651, 1978 · WM. Golebiewski et al., Chem. Comm., 1509, 1983 · K. Saito et al., Phytochemistry, 27, 3715, 1988(ir,nmr,ms) · K. Saito et al., CA, 114, 203603, 1990 · MH. Mohamed et al., J. Nat. Prod., 53, 1578, 1990 · GH. Verdoorn et al., Phytochemistry, 29, 1297, 1990