코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Hyoscyamine

다른이름들 

Tropine tropate (S-form) Daturine Duboisine

함유 천연물 

Atropa belladonna L.[벨라도나](전가초(顚茄草))
Datura alba Rumph.ex Nees[]()
Datura inermis Jacq.[-]()
Datura inoxia Mill.[-]()
Datura meteloides Dunal[털독말풀(Teol-dok-mal-pul)](양금화(洋金花),만타라자(曼陀羅子))
Datura stramonium L. var. stramonium[흰독말풀(Huin-dok-mal-pul)]()
Hyoscyamus niger L.[사리풀(Sa-ri-pul)](천선자(天仙子))
Lycium barbarum L.[](구기(枸杞))
Scopolia japonica Maxim.[미치광이풀(Mi-chi-gwang-i-pul)](동낭탕(東낭탕))

분 자 식 

C₁₇H₂₃NO₃

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

289.378

녹 는 점 

108-111°C

생리학적효과 

Anticholinergic. Antimuscarinic agent with approx. twice potency of atropine. Spasmolytic agent. Toxicity: Adverse effects on CNS and peripheral nerves. Adverse ocular effects. Can cause death. LD50 (mus, ivn) 95 mg/kg.

굴 절 율 

[α]15 D = -22°( 50% EtOH aq.)

MASS_CHART 

M+= 289, m/z= 140, 124(100), 96, 94, 83, 82, 67, 42

참고문헌 

· W. Evans et al., Phytochemistry, 11, 2527, 1972 · Y. Yamada, Plant. Cell. Rep., 1, 101, 1982 · HM. Fales et al., J. Am. Chem. Soc., 92, 1590, 1970 · J. Het. Chem., 14, 225, 1977 · Y. Gessler et al., Pharm. Acta Helv., 30, 279, 1955