코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Glaucine

다른이름들 

O-Methylthalicmidine Boldine dimethyl ether 1,2,9,10-Tetramethoxyporphine

함유 천연물 

Corydalis yanhusuo W. T. Wang[](연호색(延胡索))

분 자 식 

C₂₁H₂₅NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

355.438

생리학적효과 

Antithrombotic, analgesic and antiinflammatory activity. Antifungal agent. Produces narcosis and convulsions in animals, also hypotension and respiratory depression. Antitussive agent with similar potency to Codeine. Mild muscle relaxant.

UV_CHART 

(λmax, nm) (EtOH):218(4.58), 281(4.18), 303(4.16)

HNMR_CHART 

(CDCl3,600 MHz) δ:3.12(H4 alpha), 2.67(H4 beta), 3.02(H5 alpha), 2.45(H5 beta), 3.03(H6a), 3.01(H7 alpha), 2.57(H7 beta)

CNMR_CHART 

(CDCl3) δ: 144.2, 126.8, 127.2, 151.8, 110.4, 128.8, 29.2, 53.3, 43.4, 62.5, 34.5, 129.3, 110.9, 148.0, 147.4, 111.6, 124.4

MASS_CHART 

M+= 355, m/z= 354, 340, 338, 324, 297, 281

참고문헌 

· K. Suto et al., Chem. Pharm. Bull., 33, 12, 5369, 1985 · T. Hu et al., Nan-Ching Yao Hsueh Yuan Hsueh Pao, 16, 2, 7, 1985 · KM. Kerr et al., J. Nat. Prod., 49, 576, 1986(pmr) · M. Shamma et al., J. Nat. Prod., 42, 437, 1979(cmr) · A. Cave et al., J. Nat. Prod., 38, 275, 1975(uv,ir,ms)