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▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
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성 분 명 |
Hypaconitine |
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다른이름들 |
Deoxymesaconitine
Japaconitine B1
Japaconitine C
Japaconitine C1 |
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함유 천연물 |
Aconitum carmichaeli Deb.[오두(烏頭)](부자(附子),흑순편(黑順片),백부편(白附片),염부자(鹽附子))
Aconitum ciliare DC.[선덩굴바꽃(Seon-deong-gul-ba-kkot)](초오(草烏))
Aconitum kusnezoffii Rchb.[이삭바꽃(I-sak-ba-kkot)]()
Aconitum proliferum Nakai[싹눈바꽃(Ssang-nun-ba-kkot)]() |
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분 자 식 |
C33H45NO10 |
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화학족 분류 |
알칼로이드(alkaloid); |
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분 자 량 |
615.727 |
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녹 는 점 |
197-198(dec.)°C MeOH |
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굴 절 율 |
[α]17 D = +22.4°( CHCl3) |
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UV_CHART |
(λmax, nm) (EtOH):228.9(4.1), 271.6(3.0) |
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HNMR_CHART |
(CDCl3,80 MHz) δ:1.37(3H,s,CH3CO), 2.33(3H,s,NMe), 3.15(3H,s,MeO), 3.27(6H,s,2xMeO), 3.72(3H,s,MeO), 7.4-7.5(3H,m,arom.), 7.9-8.1(2H,m,arom.) |
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CNMR_CHART |
(CDCl3,20 MHz) δ: 85.1, 26.3, 34.9, 39.3, 48.4, 83.3, 44.6, 92.0, 44.0, 41.2, 50.0, 36.5, 74.1, 78.8, 90.3, 62.2, 80.2, 56.2, 42.4, 56.2, 60.8, 58.9, 21.3, 172.1 |
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MASS_CHART |
EIm/z= 584, 555, 524, 496, 450, 404, 238, 222, 192, 164, 133, 105(100), 77 |
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참고문헌 |
· R. Majima et al., Justus Liebigs Ann. Chem., 476, 171, 1929
· BS. Chung et al., Kor. J. Pharmacogn., 18, 103, 1987
· Y. Tsuda et al., Annalen, 680, 88, 1960
· KB. Birnbaum et al., Tetrahedron Lett., 867, 1971
· H. Hikino et al., Shoyakugaku Zasshi, 37, 68, 1983; CA, 99, 110568t
· Z. Chen et al., Heterocycles, 26, 1455, 1987
· T. Mori et al., Heterocycles, 29, 873, 1989
· XK. Wang et al., Chin. Chem. Lett., 5, 671, 1994; CA, 122, 5438w |
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